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Siterone (Cyproterone) is used to treat cancer of the prostate gland. The prostate gland is present only in males; therefore, females do not get prostate cancer.
Cyproterone blocks the effect of the male hormone testosterone in the body. This decreases the amount of testosterone produced in the body and is one way of treating this type of cancer.
In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For cyproterone, the following should be considered:
Other medical problems€”The presence of other medical problems may affect the use of cyproterone. Make sure you tell your doctor if you have any other medical problems, especially:
At first, cyproterone often causes loss of strength and energy or tiredness. However, these effects are lessened after about the third month of treatment and it is very important that you continue to receive this medication.
This medication should not be discontinued even if improvement of the disease occurs.
Dosing€”The dose of cyproterone will be different for different patients. The dose that is used may depend on a number of things, including what the medicine is being used for, the patient's body size, and whether or not other medicines are also being taken. If you are taking or receiving cyproterone at home, follow your doctor's orders or the directions on the label. If you have any questions about the proper dose of cyproterone, ask your doctor.
Oral dosage form for treating prostate cancer: is generally: 100 to 200 milligrams (mg) (2 to 4 tablets) a day divided into 2 to 3 doses and taken after meals.Missed dose€”If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.
This medicine may cause some people to become drowsy, dizzy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.
Cyproterone may cause your skin to be more sensitive to sunlight than it is normally. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking this medicine:
If you have a severe reaction from the sun, check with your doctor .
While you are taking cyproterone, be careful to limit the amount of alcohol you drink.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Less common or rare: Abdominal pain or tenderness; agitation; back pain; black, tarry stools; blisters on skin; bloody urine; blurred vision; chest pain; chills; clay colored stools; confusion; cough; dark urine; decreased appetite; decreased urine output; difficulty swallowing; dilated neck veins; dizziness; drowsiness; dry mouth; fainting or light-headedness when getting up from a lying or sitting position; fast heartbeat; fatigue; fever; flushed, dry skin; fruit-like breath odor; general feeling of discomfort or illness; hallucinations; headache, sudden and severe; hives; inability to speak; increased blood pressure; increased hunger; increased thirst; increased urination; irregular breathing; irregular heartbeat; itching; loss of consciousness; lower back/side pain; mood or mental changes; nausea and vomiting; painful or difficult urination; pains in chest, groin, or legs, especially calves of legs; puffiness or swelling of the eyelids or around the eyes, face, lips or tongue; red, thickened, or scaly skin; seizures; shortness of breath; skin rash; slurred speech; sores, ulcers, or white spots on lips or in mouth; sore throat; stiff neck; stomachache; sudden loss of coordination; sweating; swelling of feet or lower legs; swollen and/or painful glands; temporary blindness; tightness in chest; unexplained weight loss; unusual bleeding or bruising; vision changes; weakness in arm and/or leg on one side of the body, sudden and severe; wheezing; yellow eyes or skin.
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome.More Common: Decreased interest in sexual intercourse; inability to have or keep an erection; increase in sexual ability, desire, drive, or performance; increased interest in sexual intercourse; loss in sexual ability, desire, drive, or performance; swelling of the breasts or breast soreness in both females and males; unexpected or excess milk flow from breasts
Less common or rare: Bleeding, blistering, burning, coldness, or discoloration of skin; change in walking and balance; clumsiness or unsteadiness; hair loss; inability to move legs or arms; increased sensitivity of skin to sunlight; increase in bowel movements; loose stools; loss of strength or energy; muscle pain or weakness; paralysis of one side of the body; redness or other discoloration of skin; severe sunburn; soft stools; tiredness or weakness; unusual increase in hair growth; weight gain
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.